Indeterminate form of Chagas disease

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The Indeterminate Form of Chagas Disease

DOI: 10.5935/abc.20180027 The presence of diffuse fibrosis in the myocardial tissue is a characteristic of Chagas heart disease.1 The mechanisms proposed to explain such fibrosis areas vary and include direct injury by Trypanosoma cruzi to the cardiac tissue, as well as tissue ischemia due to microcirculation changes and microvascular thrombosis mediated by inflammatory2 and immune3 processes. ...

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[Indeterminate form of Chagas disease: considerations about diagnosis and prognosis].

The indeterminate form of Chagas' disease is defined by the absence of clinical, radiological and electrocardiographic manifestations of cardiac or digestive involvement in Trypanosoma cruzi chronic infected persons. When submitted to advanced cardiovascular tests, these patients may present significant abnormalities. However, the indeterminate form concept was reaffirmed as valid, since diagno...

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Scintigraphy for the detection of myocardial damage in the indeterminate form of Chagas disease.

BACKGROUND Non-invasive cardiological methods have been used for the identification of myocardial damage in Chagas disease. OBJECTIVE To verify whether the rest/stress myocardial perfusion scintigraphy is able to identify early myocardial damage in the indeterminate form of Chagas disease. METHODS Eighteen patients with the indeterminate form of Chagas Disease and the same number of normal ...

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Right Ventricular Doppler Echocardiographic Study of Indeterminate Form of Chagas Disease

BACKGROUND Patients with indeterminate form of Chagas disease/cardiac normality (ICD/CN) exhibited normal electrocardiograms and chest X-rays; however, more sophisticated tests detected some degree of morphological and functional changes in the heart. OBJECTIVE To assess the prevalence of systolic and diastolic dysfunction of the right ventricle (RV) in patients with ICD/CN. METHODS This wa...

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ژورنال

عنوان ژورنال: Memórias do Instituto Oswaldo Cruz

سال: 1999

ISSN: 0074-0276

DOI: 10.1590/s0074-02761999000700059